Proteomic Identification Principles for Fine Animal Fiber Verification
LC-MS/MS tryptic peptide analysis provides species-specific verification of fine animal fibers, overriding optical scale degradation in processed blends.
PRM Quantification
High Resolution Assay
Tandem mass spectrometry methods operating at high resolution are used to monitor and quantify multiple targeted proteins in a single run. The execution of prm quantification enables the simultaneous measurement of all fragment ions of a target hair peptide. This method provides more detailed mass measurements than traditional low-resolution assays.
Monitoring Process
The mass spectrometer isolates the target precursor ion and fragments it, then analyzes all fragment ions in a high-resolution orbitrap detector. Under prm quantification, the risk of false positives from interfering compounds in the sample matrix is reduced. This specificity is crucial for identifying closely related animal species.
Quantification Performance
Textile analysts use this technology to determine the exact proportion of luxury wool and cashmere in blended retail products. By measuring several fragment ions for each biomarker, the assay provides highly confident identification even in heavily processed or dyed fabrics. This precise quantification is used to settle commercial disputes over fibre content and to verify compliance with textile labeling laws.
Brands use these results to audit their mills and ensure that supply chains remain clean and authentic.
Data Verification
The measurement yields a complete fragment ion spectrum with high mass accuracy for each targeted peptide. Utilizing prm quantification delivers a reliable and legally defensible assessment of luxury fibre composition in finished garments.